'
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.7
USERS' SCORE
Good
Based on 6 Reviews
8.7
Supplement Facts
Serving Size: 1 MicroLingual® Tablet
Amount Per Serving
%DV
Vitamin D (as cholecalciferol)
125 mcg (5,000 IU)
625%

Top Medical Research Studies

9
Vitamin D3 correction improves pain
Role of Pre-operative Correction of Vitamin D3 Deficiency in Controlling Post-operative Bone Pain after Unicompartmental Knee Arthroplasty.
Directly assesses vitamin D's impact.
We explored the impact of vitamin D3 levels on bone pain that patients experience after undergoing unicompartmental knee arthroplasty (UKA). The study involved 240 participants who were divided into three groups based on their vitamin D status—some received treatment before surgery, some after, and others had normal levels to begin with.

By administering vitamin D3 in three doses, we aimed to see if correcting deficiencies could alleviate post-operative bone pain. Throughout the recovery period, we measured pain levels using the visual analog scale at various intervals after the surgery.

Our findings clearly demonstrated that patients who corrected their vitamin D3 deficiency before surgery reported significantly better pain control after the operation compared to those who were treated afterwards or those who started with adequate levels. This highlights the importance of testing and addressing vitamin D status prior to orthopedic procedures, showing that it is a modifiable risk factor affecting recovery.
Read More
9
Effectiveness of calcitriol combination therapy
Clinical efficacy and outcomes of calcitriol combined with bisphosphonates in the treatment of postmenopausal osteoporosis: A quasi-experimental study.
Relevant pain management study
We conducted an insightful study to analyze how combining calcitriol, a form of vitamin D, with bisphosphonates affects bone pain in postmenopausal women suffering from osteoporosis. This quasi-experimental approach allowed us to compare two groups: one treated with calcitriol alone and the other with the combination treatment.

Our findings highlighted that adding bisphosphonates to calcitriol significantly alleviated bone pain among the participants. We observed improved evaluations of joint pain through the Visual Analogue Scale/Score, indicating that patients felt much better post-treatment. Furthermore, the combination therapy enhanced the patients' overall daily living capabilities and positively influenced bone metabolism and density.

Overall, our results suggest that calcitriol combined with bisphosphonates is effective in not just relieving pain but also supporting the long-term health of bones in postmenopausal women. This approach may pave the way for improved treatment strategies for osteoporosis in this demographic.
Read More
8
Vitamin D reduces fracture risk
Association Between 25-hydroxyvitamin D Status and New Vertebral Fractures Post Percutaneous Vertebral Augmentation in Patients During Postmenopause: A Retrospective Case-control Study.
Study highlights vitamin D's importance.
We investigated the connection between vitamin D levels and the risk of new vertebral fractures in postmenopausal women who had undergone percutaneous vertebral augmentation. Through a retrospective case-control study involving patients aged 50 and older, we analyzed records to categorize participants into groups based on whether they experienced refractures and how serum levels of 25-hydroxyvitamin D (25[OH]D) influenced these outcomes.

Our findings revealed that low levels of serum 25(OH)D are linked to an increased risk of new vertebral fractures in these patients. What's noteworthy is that vitamin D plays a crucial role in maintaining bone health, and adequate levels can help reduce the likelihood of subsequent fractures after surgery. This underscores the potential importance of vitamin D supplementation for patients recovering from vertebral augmentation.

In conclusion, ensuring that patients receive appropriate vitamin D intake might be pivotal in preventing further bone pain and fractures following surgery. By addressing vitamin D deficiency, we could significantly improve bone health outcomes and enhance the quality of life for postmenopausal women recovering from vertebral fractures.
Read More

Most Useful Reviews

9.5
Life-changing effects
I bought this product around my 50th birthday after experiencing severe knee and bone pain. After considering my symptoms, I realised I was vitamin D deficient. Within weeks of taking this supplement, I experienced significant reduction in pain, allowing me to jog and climb stairs again without discomfort. This vitamin has drastically improved my life.
Read More
9.5
Improved wellbeing
I initially took Now 5000 twice daily for 15 days, but experienced terrible pains and gastrointestinal issues. After taking trimedat, my condition improved significantly. I’ve continued with these tablets and now feel much more energetic. In a month, my levels rose from 10 to 56! My doctor mentioned that test results show only 70% of actual indicators, so I plan to keep taking them for a while. Thanks to iHerb, I am on the path to better health!
Read More
9.5
Reduced breast pain
It's convenient to take, with a neutral taste. I’ve noticed an end to my breast pain before my cycle, which I had endured all my life. I have also observed an increase in the number of follicles in my ovaries, confirmed by ultrasound. It’s clear filling deficiencies makes a difference, and I'm pleased with the outcome.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.7
9
Vitamin D3 correction improves pain
Role of Pre-operative Correction of Vitamin D3 Deficiency in Controlling Post-operative Bone Pain after Unicompartmental Knee Arthroplasty.
Directly assesses vitamin D's impact.
We explored the impact of vitamin D3 levels on bone pain that patients experience after undergoing unicompartmental knee arthroplasty (UKA). The study involved 240 participants who were divided into three groups based on their vitamin D status—some received treatment before surgery, some after, and others had normal levels to begin with.

By administering vitamin D3 in three doses, we aimed to see if correcting deficiencies could alleviate post-operative bone pain. Throughout the recovery period, we measured pain levels using the visual analog scale at various intervals after the surgery.

Our findings clearly demonstrated that patients who corrected their vitamin D3 deficiency before surgery reported significantly better pain control after the operation compared to those who were treated afterwards or those who started with adequate levels. This highlights the importance of testing and addressing vitamin D status prior to orthopedic procedures, showing that it is a modifiable risk factor affecting recovery.
Read More
9
Effectiveness of calcitriol combination therapy
Clinical efficacy and outcomes of calcitriol combined with bisphosphonates in the treatment of postmenopausal osteoporosis: A quasi-experimental study.
Relevant pain management study
We conducted an insightful study to analyze how combining calcitriol, a form of vitamin D, with bisphosphonates affects bone pain in postmenopausal women suffering from osteoporosis. This quasi-experimental approach allowed us to compare two groups: one treated with calcitriol alone and the other with the combination treatment.

Our findings highlighted that adding bisphosphonates to calcitriol significantly alleviated bone pain among the participants. We observed improved evaluations of joint pain through the Visual Analogue Scale/Score, indicating that patients felt much better post-treatment. Furthermore, the combination therapy enhanced the patients' overall daily living capabilities and positively influenced bone metabolism and density.

Overall, our results suggest that calcitriol combined with bisphosphonates is effective in not just relieving pain but also supporting the long-term health of bones in postmenopausal women. This approach may pave the way for improved treatment strategies for osteoporosis in this demographic.
Read More
8
Vitamin D reduces fracture risk
Association Between 25-hydroxyvitamin D Status and New Vertebral Fractures Post Percutaneous Vertebral Augmentation in Patients During Postmenopause: A Retrospective Case-control Study.
Study highlights vitamin D's importance.
We investigated the connection between vitamin D levels and the risk of new vertebral fractures in postmenopausal women who had undergone percutaneous vertebral augmentation. Through a retrospective case-control study involving patients aged 50 and older, we analyzed records to categorize participants into groups based on whether they experienced refractures and how serum levels of 25-hydroxyvitamin D (25[OH]D) influenced these outcomes.

Our findings revealed that low levels of serum 25(OH)D are linked to an increased risk of new vertebral fractures in these patients. What's noteworthy is that vitamin D plays a crucial role in maintaining bone health, and adequate levels can help reduce the likelihood of subsequent fractures after surgery. This underscores the potential importance of vitamin D supplementation for patients recovering from vertebral augmentation.

In conclusion, ensuring that patients receive appropriate vitamin D intake might be pivotal in preventing further bone pain and fractures following surgery. By addressing vitamin D deficiency, we could significantly improve bone health outcomes and enhance the quality of life for postmenopausal women recovering from vertebral fractures.
Read More

User Reviews

USERS' SCORE
Good
Based on 6 Reviews
8.7
9.5
Improved wellbeing
I initially took Now 5000 twice daily for 15 days, but experienced terrible pains and gastrointestinal issues. After taking trimedat, my condition improved significantly. I’ve continued with these tablets and now feel much more energetic. In a month, my levels rose from 10 to 56! My doctor mentioned that test results show only 70% of actual indicators, so I plan to keep taking them for a while. Thanks to iHerb, I am on the path to better health!
Read More
9.5
Reduced breast pain
It's convenient to take, with a neutral taste. I’ve noticed an end to my breast pain before my cycle, which I had endured all my life. I have also observed an increase in the number of follicles in my ovaries, confirmed by ultrasound. It’s clear filling deficiencies makes a difference, and I'm pleased with the outcome.
Read More
9.5
Life-changing effects
I bought this product around my 50th birthday after experiencing severe knee and bone pain. After considering my symptoms, I realised I was vitamin D deficient. Within weeks of taking this supplement, I experienced significant reduction in pain, allowing me to jog and climb stairs again without discomfort. This vitamin has drastically improved my life.
Read More
8.8
Supports bone health
I ordered this for the second time. Vitamin D regulates calcium and phosphorus absorption, essential for bone health. It protects against colds, diabetes and aids in fracture healing. Symptoms of vitamin D deficiency include bone pain, loss of appetite and insomnia. I recommend taking it with calcium and fish oil, and I’m satisfied with the results.
Read More
8.8
Boosts immunity
This vitamin D3 is of excellent quality and dosage. It aids immunity and bone health and has very good absorption. I appreciate the small package and find it beneficial for allergies and autoimmune issues. It’s among the best I’ve tried!
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